[Tiginor Tablet
Atorvastatin Calcium
10 mg
Incepta Pharmaceuticals Limited
Pack Size & Price:
30's pack : ৳ 300.00 (Unit Price : ৳ 10.00)
Indications
Atorvastatin is indicated as an adjunct to diet for reduction of elevated total cholesterol, LDL-cholesterol, apolipoprotein B, and triglycerides in patients with-
Primary hypercholesterolemia- heterozygous familial and non-familial hypercholesterolemia and mixed dyslipidemia (Fredrickson types IIa and IIb)
Elevated serum TG levels (Fredrickson type IV)
Primary dysbetalipoproteinemia (Fredrickson type III) who do not respond adequately to diet.
Homozygous familial hypercholesterolemia as an adjunct to other lipid-lowering treatments (LDL apheresis) or if such treatments are unavailable.
Therapeutic Class
Other Anti-anginal & Anti-ischaemic drugs, Statins
Pharmacology
Atorvastatin is a synthetic lipid lowering agent. It is a selective, competitive inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase, the enzyme that catalyzes the conversion of HMG-CoA to mevalonate, an early and rate-limiting step in cholesterol biosynthesis.
Dosage & Administration
Patients should be placed on a standard cholesterol-lowering diet before receiving Atorvastatinand should continue on this diet during treatment with Atorvastatin. The usual starting dose for all the indications is 10mg once daily. The doses range is 10 to 80 mg once daily. Doses should be individualised according tobaseline LDL-C levels, the goal of therapy, and patient response. Adjustment of dosage should be made atintervals of 4 weeks or more. Doses may be given at anytime of day with or without food.
Children: Treatment experience in a paediatric population with dose of Atorvastatin up to 80 mg/day is limited.]
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